Methanol → [3-(4-Chloro-2-hydroxymethyl-phenoxy)-4-methoxy-phenyl]acetic acid ethyl ester

Reaction equation

[BH4-:25].[CH2:1]([CH3:2])[O:3][C:4]([CH2:5][c:6]1[cH:7][c:8]([O:14][c:15]2[c:16]([CH:22]=[O:23])[cH:17][c:18]([Cl:21])[cH:19][cH:20]2)[c:9]([O:12][CH3:13])[cH:10][cH:11]1)=[O:24].[CH3:27][OH:28].[Na+:26]>>[CH2:1]([CH3:2])[O:3][C:4]([CH2:5][c:6]1[cH:7][c:8]([O:14][c:15]2[c:16]([CH2:22][OH:23])[cH:17][c:18]([Cl:21])[cH:19][cH:20]2)[c:9]([O:12][CH3:13])[cH:10][cH:11]1)=[O:24]

Participants

Reactant 4

HCID 887Methanol

HCID 923Sodium Ion

HCID 28123Borohydride

HCID 58237578[3-(4-Chloro-2-formyl-phenoxy)-4-methoxy-phenyl]-acetic acid ethyl ester

Product 1

HCID 58237450[3-(4-Chloro-2-hydroxymethyl-phenoxy)-4-methoxy-phenyl]acetic acid ethyl ester

Sources & evidence

ORD record: ord-cfff2a016dfa45b8a7c203e1326a9ddb
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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