HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic acid, azido-, ethyl ester → Methyl (2Z,4E)-2-Azido-5-(4-isopropylphenyl)penta-2,4-dienoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic acid, azido-, ethyl ester | HCID 69480 | — |
| Reactant | 4-Isopropylcinnamaldehyde | HCID 5354897 | — |
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Methyl (2Z,4E)-2-Azido-5-(4-isopropylphenyl)penta-2,4-dienoate | HCID 59338838 | — |
Reaction Steps
Following General Procedure I, a 1.34 M solution of NaOMe in methanol (30 ml), (E)-3-(4-isopropylphenyl)acrylaldehyde (Compound 110, 1.4 g, 8.0 mmol) and ethyl azidoacetate (12 ml, 40.2 mmol) in MeOH (20 ml) were reacted to produce the title compound as a solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07728014B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-592b442687364ab1abccb3c7162513dc |
| Source note | uspto-grants-2010_06 |