Cinchophen → 2-Phenylquinoline-4-carbonyl chloride

HRID 1259844

Reaction equation

HRID 1259844 reaction equation
[C:1]1([C:7]2[CH:16]=[C:15]([C:17]([OH:19])=O)[C:14]3[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=3)[N:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.S(Cl)([Cl:22])=O>>[C:1]1([C:7]2[CH:16]=[C:15]([C:17]([Cl:22])=[O:19])[C:14]3[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=3)[N:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 8593CinchophenHCID 24386Thionyl Chloride

Product 1

HCID 27604092-Phenylquinoline-4-carbonyl chloride

Procedure

2-phenyl-4-quinolinecarbonyl chloride was synthesized from commercially available 2-phenyl-4-quinolinecarboxylic acid and thionyl chloride according to a routine method.

Sources & evidence

ORD record
ord-1a6ba8edd2f34d55ac80376a7a953c4d
Source dataset
uspto-grants-2013_06
Patent number
US08466290B2

Linked notes

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