1-(Bromomethyl)-2-chloro-4-(methylsulfonyl)benzene → 1-Bromomethyl-2-chloro-4-ethanesulfonyl-benzene

Reaction equation

[Br:1][CH2:2][C:3]1[CH:8]=[CH:7][C:6]([S:9]([CH3:12])(=[O:11])=[O:10])=[CH:5][C:4]=1[Cl:13].[CH2:14](S([O-])=O)C.[Na+]>>[Br:1][CH2:2][C:3]1[CH:8]=[CH:7][C:6]([S:9]([CH2:12][CH3:14])(=[O:11])=[O:10])=[CH:5][C:4]=1[Cl:13]

Participants

Reactant 2

HCID 27610831-(Bromomethyl)-2-chloro-4-(methylsulfonyl)benzene

HCID 22986214Sodium Ethanesulfinate

Product 1

HCID 672198261-Bromomethyl-2-chloro-4-ethanesulfonyl-benzene

Procedure

The titled compound is prepared analogously to 1-bromomethyl-2-chloro-4-methanesulfonyl-benzene by replacing sodium methanesulfinate with sodium ethanesulfinate.

Sources & evidence

ORD record: ord-4d473276a5244ca2bb41295b2cc6c1c0
Source dataset: uspto-grants-2013_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08470848B2

Reaction notes

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