2-Methoxy-4-nitrobenzonitrile → 4-Cyano-3-methoxybenzenesulfonyl chloride

HRID 1260675Notes

Reaction equation

HRID 1260675 reaction equation
[C:1]([C:3]1[CH:8]=[CH:7][C:6]([S:9]([Cl:12])(=[O:11])=[O:10])=[CH:5][C:4]=1[O:13][CH2:14]C)#[N:2].COC1C=C([N+]([O-])=O)C=CC=1C#N>>[C:1]([C:3]1[CH:8]=[CH:7][C:6]([S:9]([Cl:12])(=[O:11])=[O:10])=[CH:5][C:4]=1[O:13][CH3:14])#[N:2]

Participants

3

Reactant 2

HCID 2918672-Methoxy-4-nitrobenzonitrileHCID 552808794-Cyano-3-ethoxybenzene-1-sulfonyl chloride2×

Product 1

HCID 552792354-Cyano-3-methoxybenzenesulfonyl chloride

Procedure

The titled compound was prepared analogously to 4-cyano-3-ethoxy-benzenesulfonyl chloride (Intermediate 127c) by replacing 2-ethoxy-4-nitro-benzonitrile with 2-methoxy-4-nitro-benzonitrile.

Sources & evidence

ORD record
ord-27523bd400d144069834198676b49a46
Source dataset
uspto-grants-2013_06
Patent number
US08470848B2

Reaction notes

Loading…