2,5-Difluorobenzylamine → HCID 68662151, compound

HRID 1260871

Reaction equation

HRID 1260871 reaction equation
[C:1]([CH:3]([CH:7]1[C:11]([Cl:12])=[C:10](Cl)C(=O)O1)[C:4]([NH2:6])=[O:5])#[N:2].[F:15][C:16]1[CH:21]=[CH:20][C:19]([F:22])=[CH:18][C:17]=1[CH2:23][NH2:24]>>[ClH:12].[Cl:12][C:11]1[CH:7]=[C:3]([C:4]([NH2:6])=[O:5])[C:1](=[NH:2])[N:24]([CH2:23][C:17]2[CH:18]=[C:19]([F:22])[CH:20]=[CH:21][C:16]=2[F:15])[CH:10]=1

Participants

3

Reactant 2

HCID 1235892,5-DifluorobenzylamineHCID 5417922-Cyano-2-(3,4-dichloro-5(2H)-oxo-2-furyl)acetamide

Product 1

HCID 68662151HCID 68662151, compound

Procedure

According to the method of Example 160, 2-cyano-2-(3,4-dichloro-5-oxo-2,5-dihydrofuran-2-yl)acetamide was reacted with 1-(2,5-difluorophenyl)methanamine to give the title compound.

Sources & evidence

ORD record
ord-70f01ebf3eb04cda98a2cd9f6e129001
Source dataset
uspto-grants-2013_06
Patent number
US08470859B2

Linked notes

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