3,4-Dichloroaniline → 2-[(3,4-Dichlorophenyl)amino]phenylacetic acid

Reaction equation

Br[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([OH:11])=[O:10].[Cl:12][C:13]1[CH:14]=[C:15]([CH:17]=[CH:18][C:19]=1[Cl:20])[NH2:16]>>[Cl:12][C:13]1[CH:14]=[C:15]([NH:16][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=2[CH2:8][C:9]([OH:11])=[O:10])[CH:17]=[CH:18][C:19]=1[Cl:20]

Participants

Reactant 2

HCID 72573,4-Dichloroaniline

HCID 877542-Bromophenylacetic acid

Product 1

HCID 147629542-[(3,4-Dichlorophenyl)amino]phenylacetic acid

Procedure

In the manner described in example 3, 2-bromophenylacetic acid was condensed with 3,4-dichloroaniline to yield 2-[(3,4-dichlorophenyl)amino]phenylacetic acid.

Sources & evidence

ORD record: ord-33a841516cc6483398e6e9a353e1f84a
Source dataset: uspto-grants-2003_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06552077B2

Reaction notes

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