Acetone → Sodium imidazo-[1,2-a]-quinoxaline-2-carboxylate
Reaction equation
[OH-].[Na+:2].[CH:3]1[N:7]2[C:8]3[C:13]([N:14]=[CH:15][C:6]2=[N:5][C:4]=1[C:16]([OH:18])=[O:17])=[CH:12][CH:11]=[CH:10][CH:9]=3.CC(C)=O>O>[CH:3]1[N:7]2[C:8]3[C:13]([N:14]=[CH:15][C:6]2=[N:5][C:4]=1[C:16]([O-:18])=[O:17])=[CH:12][CH:11]=[CH:10][CH:9]=3.[Na+:2]Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
Aqueous 2 N sodium hydroxide solution was added dropwise to a stirred suspension of 2 g of imidazo-[1,2-a]-quinoxaline-2-carboxylic acid in 20 ml of water until dissolution occured at a pH of 9-10. Acetone was added to the mixture to cause precipitation and the mixture was filtered to obtain 1.8 g of sodium imidazo-[1,2-a]-quinoxaline-2-carboxylate melting at >300° C.
Workup
- customprecipitation
- filtrationthe mixture was filtered
Sources & evidence
- ORD record
- ord-6010b13c11914ebc81748009d6ff8a06
- Source dataset
- uspto-grants-1981_03
- Patent number
- US04254123
Reaction notes
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