(3-Iodopropyl)cyclohexane → (Pent-4-yn-1-yl)cyclohexane

Reaction equation

[CH:1]1([CH2:7][CH2:8][CH2:9]I)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[C-:11]#[C-:12].[Na+].[Na+]>>[CH:1]1([CH2:7][CH2:8][CH2:9][C:11]#[CH:12])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

Reactant 2

HCID 22279825(3-Iodopropyl)cyclohexane

HCID 178463197HCID 178463197, compound

Product 1

HCID 15172912(Pent-4-yn-1-yl)cyclohexane

Procedure

The title compound was synthesized using 3-cyclohexyl-1-iodopropane and sodium acetylide by conducting the reactions similar to those mentioned in Reference example 29.

Sources & evidence

ORD record: ord-271cb295507b49b48b410f6b5ba81f8c
Source dataset: uspto-grants-2007_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07199150B2

Reaction notes

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