6-Hydroxy-1-naphthoic acid → 6-Hydroxy-5-[(2-methoxyphenyl)-morpholin-4-yl-methyl]-naphthalene-1-carboxylic acid
Reaction equation
[OH:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[C:8]([C:12]([OH:14])=[O:13])=[CH:7][CH:6]=[CH:5]2.[Cl-].[CH3:16][O:17][C:18]1[CH:30]=[CH:29][CH:28]=[CH:27][C:19]=1[CH:20]=[N+:21]1[CH2:26][CH2:25][O:24][CH2:23][CH2:22]1>>[OH:1][C:2]1[C:3]([CH:20]([C:19]2[CH:27]=[CH:28][CH:29]=[CH:30][C:18]=2[O:17][CH3:16])[N:21]2[CH2:26][CH2:25][O:24][CH2:23][CH2:22]2)=[C:4]2[C:9](=[CH:10][CH:11]=1)[C:8]([C:12]([OH:14])=[O:13])=[CH:7][CH:6]=[CH:5]2Participants
3
Procedure
The preparation was carried out in accordance with general synthesis instructions 4 from 6-hydroxy-1-naphthoic acid and 4-(2-methoxy-benzylidene)-morpholin-4-ium chloride, which had been prepared in accordance with example 28.
Workup
- customhad been prepared in accordance with example 28