Ethyl 4-methoxycinnamate → 4-(4-methoxyphenyl)dihydro-2H-pyran-2,6(3H)-dione

HRID 1272274

Reaction equation

HRID 1272274 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH:9]=[CH:10][C:11]([O:13][CH2:14][CH3:15])=[O:12])=[CH:5][CH:4]=1.C(OCC)(=[O:18])C.CCCCCC>>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([CH:9]2[CH2:15][C:14](=[O:18])[O:13][C:11](=[O:12])[CH2:10]2)=[CH:7][CH:8]=1

Participants

3

Reactant 2

HCID 74728Ethyl 4-methoxycinnamateHCID 21226206Ethyl acetate hexane

Product 1

HCID 2979014-(4-methoxyphenyl)dihydro-2H-pyran-2,6(3H)-dioneYield 38%

Procedure

Using ethyl 3-(4-methoxyphenyl)-2-propenoate, the title compound was synthesized in the same manner as in Reference Example 5. Yield 38%. mp. 144–149° C. (ethyl acetate-hexane).

Sources & evidence

ORD record
ord-83565cf6d1a74effb0aca3d1b13b735a
Source dataset
uspto-grants-2007_04
Patent number
US07208495B2

Linked notes

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