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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 127248Generated: October 26, 2026

4-Methylbenzyl chloride → 1-(4-Methylbenzyl)-4-(2-hydroxy-3-n-hexadecyloxypropyl)-piperazine

https://huagongshe.com/reaction/127248

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Methylbenzyl chlorideHCID 7722—
Reactant1-(2-Hydroxy-3-n-hexadecyloxypropyl)-piperazineHCID 13037790—
Product1-(4-Methylbenzyl)-4-(2-hydroxy-3-n-hexadecyloxypropyl)-piperazineHCID 13037795—

Reaction Steps

Following the procedure of Example 5, 1-(2-hydroxy-3-n-hexadecyloxypropyl)-piperazine was reacted with 4-methylbenzyl chloride to form 1-(4-methylbenzyl)-4-(2-hydroxy-3-n-hexadecyloxypropyl)-piperazine, mp 238°-239° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04255426
Source datasetuspto-grants-1981_03
ORD IDord-ec00e716bff843f9bfa99578beac3d4b
Source noteuspto-grants-1981_03