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(S)-Methyl 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-hydroxypropanoate → O-[9-(4-Methylphenyl)-9H-thioxanthen-9-yl]-L-serine

HRID 1275752
Notes
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Reaction equation

HRID 1275752 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2([OH:22])[C:21]3[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=3[S:15][C:14]3[C:9]2=[CH:10][CH:11]=[CH:12][CH:13]=3)=[CH:4][CH:3]=1.C[O:24][C:25](=[O:47])[C@H:26]([CH2:45]O)[NH:27]C(OCC1C2C=CC=CC=2C2C1=CC=CC=2)=O>>[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2([O:22][CH2:45][C@@H:26]([C:25]([OH:47])=[O:24])[NH2:27])[C:9]3[CH:10]=[CH:11][CH:12]=[CH:13][C:14]=3[S:15][C:16]3[C:21]2=[CH:20][CH:19]=[CH:18][CH:17]=3)=[CH:6][CH:7]=1
ParticipantsProcedureSources & evidenceReaction notes

Participants

3

Reactant 2

HCID 7020783(S)-Methyl 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-hydroxypropanoateHCID 122156859-(4-methylphenyl)-9H-thioxanthen-9-ol

Product 1

HCID 54499948O-[9-(4-Methylphenyl)-9H-thioxanthen-9-yl]-L-serine

Procedure

from 9-(4-methylphenyl)-9H-thioxanthen-9-ol (Example 1p) and Nα -(9-fluorenylmethoxycarbonyl)-L-serine methyl ester;

Sources & evidence

ORD record
ord-4fac5a1f20464ee5ad7bd605739971c4
Source dataset
uspto-grants-2000_12
DOI
10.6084/m9.figshare.5104873.v1
Patent number
US06162824

Reaction notes

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On this pageParticipantsProcedureSources & evidenceReaction notes