9-(2-Methylphenyl)-9h-fluoren-9-ol → HCID 54167192, compound

Reaction equation

[CH3:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1([OH:21])[C:20]2[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=2[C:14]2[C:9]1=[CH:10][CH:11]=[CH:12][CH:13]=2.C[O:23][C:24](=[O:47])[C@H:25]([C@@H:44]([CH3:46])O)[NH:26]C(OCC1C2C=CC=CC=2C2C1=CC=CC=2)=O>>[CH3:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1([O:21][C@H:44]([CH3:46])[C@@H:25]([C:24]([OH:47])=[O:23])[NH2:26])[C:20]2[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=2[C:14]2[C:9]1=[CH:10][CH:11]=[CH:12][CH:13]=2

Participants

Reactant 2

HCID 2919429-(2-Methylphenyl)-9h-fluoren-9-ol

HCID 11164107HCID 11164107, compound

Product 1

HCID 54167192HCID 54167192, compound

Procedure

from 9-(2-methylphenyl)-9H-fluoren-9-ol (Example 3g) and Nα -(9-fluorenyl methoxycarbonyl )-L-threonine methyl ester;

Sources & evidence

ORD record: ord-12ccbcebc7b34a58a9ef24a1cf2410ab
Source dataset: uspto-grants-2000_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06162824

Reaction notes

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