9-(4-Methoxyphenyl)-9H-fluoren-9-ol → HCID 54262931, compound

Reaction equation

[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2([OH:22])[C:21]3[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=3[C:15]3[C:10]2=[CH:11][CH:12]=[CH:13][CH:14]=3)=[CH:5][CH:4]=1.C[O:24][C:25](=[O:48])[C@H:26]([C@@H:45]([CH3:47])O)[NH:27]C(OCC1C2C=CC=CC=2C2C1=CC=CC=2)=O>>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([C:9]2([O:22][C@H:45]([CH3:47])[C@@H:26]([C:25]([OH:48])=[O:24])[NH2:27])[C:10]3[CH:11]=[CH:12][CH:13]=[CH:14][C:15]=3[C:16]3[C:21]2=[CH:20][CH:19]=[CH:18][CH:17]=3)=[CH:7][CH:8]=1

Participants

Reactant 2

HCID 2762179-(4-Methoxyphenyl)-9H-fluoren-9-ol

HCID 11164107HCID 11164107, compound

Product 1

HCID 54262931HCID 54262931, compound

Procedure

from 9-(4-methoxyphenyl)-9H-fluoren-9-ol (Example 3n) and Nα -(9-fluorenylmethoxycarbonyl)-L-threonine methyl ester;

Sources & evidence

ORD record: ord-ae65bba21ea2487dae9097c57229a898
Source dataset: uspto-grants-2000_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06162824

Reaction notes

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