Ammonia → HCID 13566351, compound
Reaction equation
C([O:3][C:4]([C:6]1[S:7][C:8]([S:11][CH3:12])=[N:9][N:10]=1)=O)C.[NH3:13]>C(O)C>[CH3:12][S:11][C:8]1[S:7][C:6]([C:4]([NH2:13])=[O:3])=[N:10][N:9]=1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
11.8 g of 5-methylthio-1,3,4-thiadiazole-2-carboxylic acid ethylester which is the compound obtained in Example 10, were mixed with 50 ml ethanol and 50 ml of a 25% aqueous ammonia solution whereupon the mixture was heated for 15 minutes on a steam bath. After cooling part of the reaction product precipitated. The precipitation was completed by adding ice water. The precipitate was then removed by suction and dried in a vacuum.
Workup
- temperaturewas heated for 15 minutes on a steam bath
- temperatureAfter cooling part of the reaction product
- customprecipitated
- customThe precipitation
- additionby adding ice water
- customThe precipitate was then removed by suction
- customdried in a vacuum
Sources & evidence
- ORD record
- ord-2664f60a5d0346c192abd68f779b58e5
- Source dataset
- uspto-grants-1981_07
- Patent number
- US04279907
Reaction notes
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