Hydrazine → Veratrohydrazide
Reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:10]=[CH:11][C:12]=1[O:13][CH3:14])[C:6](OC)=[O:7].[NH2:15][NH2:16]>O>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:10]=[CH:11][C:12]=1[O:13][CH3:14])[C:6]([NH:15][NH2:16])=[O:7]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
A mixture of 9.8 g (0.05 mol) of methyl 3,4-dimethoxybenzoate and 15 ml of 85% water containing hydrazine was refluxed for 2.5 hours with stirring. The reaction mixture was cooled and the crystals formed were recovered by filtration and washed with water to provide 3,4-dimethoxybenzoic acid hydrazide. The yield was quantitative.
Workup
- temperaturewas refluxed for 2.5 hours
- temperatureThe reaction mixture was cooled
- customthe crystals formed
- filtrationwere recovered by filtration
- washwashed with water
Sources & evidence
- ORD record
- ord-347cd166ced1414490107c6db4607ad9
- Source dataset
- uspto-grants-1981_07
- Patent number
- US04279982
Reaction notes
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