3-(Dimethylamino)-1-(furan-3-yl)prop-2-en-1-one → 3-Bromo-7-(3-furyl)pyrazolo[1,5-a]pyrimidine

HRID 1278217

Reaction equation

HRID 1278217 reaction equation
C[N:2]([CH3:12])[CH:3]=[CH:4][C:5]([C:7]1[CH:11]=[CH:10][O:9][CH:8]=1)=O.NC1[C:18]([Br:19])=[CH:17][NH:16][N:15]=1>C(O)(=O)C>[Br:19][C:18]1[CH:17]=[N:16][N:15]2[C:5]([C:7]3[CH:11]=[CH:10][O:9][CH:8]=3)=[CH:4][CH:3]=[N:2][C:12]=12

Participants

4

Reactant 2

HCID 14746553-(Dimethylamino)-1-(furan-3-yl)prop-2-en-1-oneHCID 178509245HCID 178509245, compound

Product 1

HCID 211630723-Bromo-7-(3-furyl)pyrazolo[1,5-a]pyrimidine

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

A mixture of 0.01 mole of 3-dimethylamino-1-(3-furyl)-2-propen-1-one and 0.01 mole of 3-amino-4-bromopyrazole in glacial acetic acid is heated at reflux temperature for 6 hours. The solvent is removed to give the product of the example.

Workup

  1. temperatureis heated
  2. temperatureat reflux temperature for 6 hours
  3. customThe solvent is removed
  4. customto give the product of the example

Sources & evidence

ORD record
ord-06aa58a8de164230ab4a994e1affe347
Source dataset
uspto-grants-1981_07
Patent number
US04281000

Linked notes

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