Mesityl oxide → 2-METHYL-2-(t-AMYLPEROXY)-4-PENTANONE

HRID 127860

Reaction equation

[O:1]=[C:2]([CH:4]=[C:5]([CH3:7])[CH3:6])[CH3:3].[C:8]([O:13][OH:14])([CH2:11][CH3:12])([CH3:10])[CH3:9]>CCCCCC>[CH3:6][C:5]([O:14][O:13][C:8]([CH2:11][CH3:12])([CH3:10])[CH3:9])([CH2:4][C:2](=[O:1])[CH3:3])[CH3:7]

Participants

Conditions

Temperature: 40 °C

Procedure

A reaction mixture of 11.8 g (0.12 mole) of mesityl oxide, 30 g of Amberlyst 15® sulfonic acid type ion-exchange resin, and 15.6 g (0.15 mole) of 89% t-amyl hydroperoxide was stirred at 25°-30° C. for 20 hours and at 40° C. for 1 hour. Hexane was added and the ion-exchange resin separated by filtration. The filtrate was washed with sodium bisulfite solution and with water and the organic layer dried over anhydrous magnesium sulfate. The hexane solvent was removed under reduced pressure and the 11.7 g of recovered product identified by its infrared spectrum.

Workup

customthe ion-exchange resin separated by filtration
washThe filtrate was washed with sodium bisulfite solution and with water
dry with materialthe organic layer dried over anhydrous magnesium sulfate
customThe hexane solvent was removed under reduced pressure

Sources & evidence

ORD record: ord-ec39ff7c82754dec9fff141dc2de07ed
Source dataset: uspto-grants-1981_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04257985

Linked notes

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