Dioctadecylamine → HCID 20433003, compound

HRID 127992

Reaction equation

HRID 127992 reaction equation
[CH2:1]([NH:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH3:37])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18].Br[CH2:39][CH2:40][CH2:41][C:42]([O:44][CH2:45][CH3:46])=[O:43]>C1(C)C=CC=CC=1>[CH2:20]([N:19]([CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18])[CH2:39][CH2:40][CH2:41][C:42]([O:44][CH2:45][CH3:46])=[O:43])[CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH3:37]

Participants

4

Reactant 2

HCID 66989DioctadecylamineHCID 76300Ethyl 4-bromobutyrate

Product 1

HCID 20433003HCID 20433003, compoundYield 58.2%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

A solution of dioctadecylamine (5.2 g., 0.01 mole), ethyl 4-bromobutyrate (1.95 g., 0.01 mole) and toluene (50 ml.) is heated at reflux for sixteen hours, then cooled and concentrated in vacuo to a semi-solid oil. The oil is triturated with ethylacetate, filtered, and the filtrate washed with water, then dried (Na2SO4). Removal of the solvent gives the product as an oil (3.7 g.).

Workup

  1. temperatureat reflux for sixteen hours
  2. temperaturecooled
  3. concentrationconcentrated in vacuo to a semi-solid oil
  4. customThe oil is triturated with ethylacetate
  5. filtrationfiltered
  6. washthe filtrate washed with water
  7. dry with materialdried (Na2SO4)
  8. customRemoval of the solvent

Sources & evidence

ORD record
ord-24c64bf11f244c4e8505596e5ea82237
Source dataset
uspto-grants-1981_03
Patent number
US04258061

Linked notes

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