Hydrazine → N-(4-nitrophenyl)hydrazinecarboxamide
Reaction equation
[NH2:1][NH2:2].[N+:3]([C:6]1[CH:11]=[CH:10][C:9]([NH:12][C:13](=[O:21])OC2C=CC=CC=2)=[CH:8][CH:7]=1)([O-:5])=[O:4]>O1CCOCC1>[N+:3]([C:6]1[CH:11]=[CH:10][C:9]([NH:12][C:13]([NH:1][NH2:2])=[O:21])=[CH:8][CH:7]=1)([O-:5])=[O:4]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
Hydrazine (1.18 mol) was added dropwise over a 1 hour period to a solution of intermediate (1) in 1,4-dioxane (1000 ml) and the mixture was stirred and refluxed overnight. The mixture was cooled and filtered off, yielding N-(4-nitro-phenyl)hydrazinecarboxamide (intermediate 2).
Workup
- temperaturerefluxed overnight
- temperatureThe mixture was cooled
- filtrationfiltered off
Sources & evidence
- ORD record
- ord-4947ae4ea09a4d879cbc317be6233219
- Source dataset
- uspto-grants-2002_09
- Patent number
- US06451802B1
Reaction notes
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