Ammonium Chloride → Pyridine, 2,3,5-trichloro-

HRID 128054Notes

Reaction equation

HRID 128054 reaction equation
[Cl:1][C:2]1[C:7]([Cl:8])=[C:6](Cl)[C:5]([Cl:10])=[CH:4][N:3]=1.[Cl-].[NH4+]>[Zn]>[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][C:5]([Cl:10])=[CH:4][N:3]=1

Participants

4

Reactant 2

HCID 25517Ammonium ChlorideHCID 760512,3,4,5-Tetrachloropyridine

Product 1

HCID 27666Pyridine, 2,3,5-trichloro-Yield 78%

Reagents, catalysts & solvents 1

HCID 23994ZincCatalyst

Procedure

By the method described in Example 1, 11.0 g (0.05 mol) of 2,3,4,5-tetrachloropyridine, 4.4 g (0.065 gram atom) of zinc dust (96%) and 4.0 g (0.075 mol) of ammonium chloride are reacted to yield 7.1 g (78% of theory) of 2,3,5-trichloropyridine, m.p. 36°-40° C., which contains, according to gas-chromatographical analysis, 79.2% of 2,3,5-trichloropyridine, 11.8% of 2,3,4,5-tetrachloropyridine and 6.6% of unknown products.

Workup

  1. customare reacted

Sources & evidence

ORD record
ord-2b2935851bad4e46b5f50bd915c78a79
Source dataset
uspto-grants-1981_03
Patent number
US04258194

Reaction notes

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