Sulfuric Acid → 2-Methylchromone
Reaction equation
S(=O)(=O)(O)O.[C:6]([CH2:9][C:10]([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)=[O:11])(=[O:8])[CH3:7]>O>[CH3:7][C:6]1[O:8][C:13]2[CH:14]=[CH:15][CH:16]=[CH:17][C:12]=2[C:10](=[O:11])[CH:9]=1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
Concentrated sulphuric acid (30 g) is added to acetyl acetophenone (15 g) obtained as above described. After cooling at room temperature, water is added until precipitation of a white powder, which is isolated by filtration under vacuum and washed with cold water. 2-methyl-4H-1-benzopyran-4-one (10 g) is obtained (m.p.=71° C.; yield=74%).
Workup
- customobtained
- customwhich is isolated by filtration under vacuum
- washwashed with cold water
Sources & evidence
- ORD record
- ord-d52e18c19c6645ee8409ed28a72c7be2
- Source dataset
- uspto-grants-2002_09
- Patent number
- US06455578B1
Reaction notes
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