1-Bromohexane → 6-(2-Ethoxyphenyl)-4,5-dihydropyridazin-3(2H)-one
Reaction equation
C(Br)CCCCC.[CH2:8]([O:14][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=1[C:21]1[CH2:22][CH2:23][C:24](=[O:27])[NH:25][N:26]=1)[CH2:9]CCCC>>[CH2:8]([O:14][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=1[C:21]1[CH2:22][CH2:23][C:24](=[O:27])[NH:25][N:26]=1)[CH3:9]Participants
3
Procedure
Similarly prepared using hexyl bromide in place of ethyl bromide was: 6-(o-Hexyloxyphenyl)-4,5-dihydro-3(2H)-pyridazinone m.p. 75°-77°C.
Workup
- customSimilarly prepared
Sources & evidence
- ORD record
- ord-cbc57cb607084aad8463be59cc2db9b0
- Source dataset
- uspto-grants-1976_08
- Patent number
- US03975388
Reaction notes
Loading…