Methyl Isocyanate → HCID 152749587, compound
Reaction equation
[CH3:1][N:2]=[C:3]=[O:4].[CH2:5]([O:7][C:8]([NH:10][C:11]([NH2:13])=[NH:12])=[O:9])[CH3:6]>O1CCOCC1>[CH3:1][NH:2][C:3]([NH:13][C:11]([NH:10][C:8]([O:7][CH2:5][CH3:6])=[O:9])=[NH:12])=[O:4]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
5.1 parts by weight of methylisocyanate were added to a suspension of 10 parts by weight of ethoxycarbonylguanidine (manufactured according to Isr. J. Chem. 8, 651 [1970] ) in 60 parts by volume of anhydrous dioxane, in the course of which the temperature rose to 45°C and the precipitate dissolved. After a short time, a crystalline precipitate separated out again, which was filtered off after cooling and washed with ether. It was dried in vacuo over P2O5 and paraffin chips.
Workup
- customrose to 45°C
- dissolutionthe precipitate dissolved
- customAfter a short time, a crystalline precipitate separated out again
- filtrationwhich was filtered off
- temperatureafter cooling
- washwashed with ether
- dry with materialIt was dried in vacuo over P2O5 and paraffin chips
Sources & evidence
- ORD record
- ord-57ca6c4a276e406886aa76d414e586c7
- Source dataset
- uspto-grants-1976_08
- Patent number
- US03975375
Reaction notes
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