HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloroacetyl chloride → Thiophene-3,4-dicarboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloroacetyl chloride | HCID 6577 | — |
| Reactant | 1H,3H-Thieno[3,4-c]furan-1,3-dione | HCID 315608 | — |
| Product | Thiophene-3,4-dicarboxylic acid | HCID 255853 | — |
Reaction Steps
A 25.5 g. portion of 3,4-thiophenedicarboxylic acid {prepared by the method of Kornfeld and Jones [J. Org. Chem., 19, 1671 (1954)]} is suspended in 50 ml. of chloroacetyl chloride and is heated at reflux for 5.5 hours. Excess chloroacetyl chloride is distilled under reduced pressure. The residue is poured into 100 ml. of water and the resulting crystals are collected to yield 16.1 g. of 3,4-thiophenedicarboxylic anhydride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04259476 |
| Source dataset | uspto-grants-1981_03 |
| ORD ID | ord-cdd40e584b9e4651ba74e24770d441ee |
| Source note | uspto-grants-1981_03 |