Ethyl chloroformate → HCID 68139647, compound

Reaction equation

[CH2:1]([C:3]1[C:12]2[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=2[N:6]=[C:5]2[CH2:13][CH2:14][NH:15][CH2:16][CH2:17][C:4]=12)[CH3:2].[Cl:18][C:19]([O:21][CH2:22][CH3:23])=[O:20]>>[ClH:18].[CH2:22]([O:21][C:19]([N:15]1[CH2:16][CH2:17][C:4]2[C:5](=[N:6][C:7]3[CH:8]=[CH:9][CH:10]=[CH:11][C:12]=3[C:3]=2[CH2:1][CH3:2])[CH2:13][CH2:14]1)=[O:20])[CH3:23]

Participants

Reactant 2

HCID 10928Ethyl chloroformate

HCID 21503554HCID 21503554, compound

Product 1

HCID 68139647HCID 68139647, compoundYield 72%

Procedure

1,2,4,5-Tetrahydro-11-ethyl-3-azepino[4,5-b]quinoline-carboxylic acid ethyl ester hydrochloride was prepared from 11-ethyl-1,2,4,5-tetrahydro-3H-azepino[4,5-b]quinoline and ethyl chloroformate analogous to Example 63.

Sources & evidence

ORD record: ord-35f88c4614fb42578958f9330f6a0d47
Source dataset: uspto-grants-1976_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US03987047

Reaction notes

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