Sodium Hydroxide → 2-Naphthalenemethanol, 6-methyl-
Reaction equation
[H-].[Al+3].[Li+].[H-].[H-].[H-].[CH3:7][C:8]1[CH:9]=[C:10]2[C:15](=[CH:16][CH:17]=1)[CH:14]=[C:13]([C:18](O)=[O:19])[CH:12]=[CH:11]2.[OH-].[Na+]>CCOCC>[CH3:7][C:8]1[CH:9]=[C:10]2[C:15](=[CH:16][CH:17]=1)[CH:14]=[C:13]([CH2:18][OH:19])[CH:12]=[CH:11]2Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
To a suspension of 2.7 g. of lithium aluminum hydride in 75 ml. of dry ether is added dropwise a solution containing 5.5 g. of 6-methyl-2-naphthoic acid in 75 ml. of dry ether. The mixture is refluxed for three hours, cooled, and treated with 10% sodium hydroxide solution. The mixture is then filtered and dried to yield 6-methyl-2-naphthalenemethanol.
Workup
- additionTo a suspension of 2.7 g
- additioncontaining 5.5 g
- temperatureThe mixture is refluxed for three hours
- temperaturecooled
- filtrationThe mixture is then filtered
- customdried
Sources & evidence
- ORD record
- ord-27060e4ca05c4ba598d92e877bac7ce5
- Source dataset
- uspto-grants-1976_10
- Patent number
- US03988457
Reaction notes
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