Acetic Acid → HCID 14795882, compound

To a solution of methyl 4-tri-n-butylstannylbenzoate (3.0 g, 7 mmol) in absolute ethanol (60 ml) was added 0.25 g KOH (9 mmol). The resulting solution was refluxed for 2 hours. The solution was cooled and poured into an ice-cold solution of acetic acid (0.64 g, 10.6 mmol) and water (100 ml). The solution was then extracted with diethyl ether (80 ml). The ether phase was washed with water (30 ml), dried over MgSO4 (5 g), filtered and evaporated under reduced pressure to afford 2.6 g (88%) of the title compound. This material was used without further purification.

1. temperatureThe resulting solution was refluxed for 2 hours
2. temperatureThe solution was cooled
3. extractionThe solution was then extracted with diethyl ether (80 ml)
4. washThe ether phase was washed with water (30 ml)
5. dry with materialdried over MgSO4 (5 g)
6. filtrationfiltered
7. customevaporated under reduced pressure

ORD record

ord-871560983abd480daa5fe2479ef7f7f5

Source dataset

uspto-grants-1998_05

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US05746997