HCID 18925402, compound → HCID 18925409, compound

Reaction equation

[N+](C1C=CSC=1C1C=CC(Cl)=CC=1)([O-])=O.[N+:16]([C:19]1[CH:23]=[CH:22][S:21][C:20]=1[C:24]1[CH:29]=[CH:28][C:27]([CH3:30])=[CH:26][CH:25]=1)([O-])=O>>[NH2:16][C:19]1[CH:23]=[CH:22][S:21][C:20]=1[C:24]1[CH:29]=[CH:28][C:27]([CH3:30])=[CH:26][CH:25]=1

Participants

Reactant 2

HCID 18925402HCID 18925402, compound

HCID 18925412HCID 18925412, compound

Product 1

HCID 18925409HCID 18925409, compoundYield 68%

Procedure

The same procedures as described in Example 3 were carried out except that 3-nitro-2-(4-chlorophenyl)thiophene was replaced by 3-nitro-2-(4-tolyl)thiophene. The yield was 68%. 1H-NMR(CDCl3, δ value):2.37(3H, s), 3.79(2H, brs), 6.54(d, J=5.1), 7.09(1H, d, J=5.1), 7.22(2H, d, J=8.1), 7.41(2H, d, J=8.1)

Sources & evidence

ORD record: ord-15f838ef91a945aba7951adad6cf8a1b
Source dataset: uspto-grants-1998_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05747518

Reaction notes

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