HCID 18925402, compound → HCID 18925420, compound

Reaction equation

[N+](C1C=CSC=1C1C=CC(Cl)=CC=1)([O-])=O.[N+:16]([C:19]1[CH:23]=[CH:22][S:21][C:20]=1[C:24]1[CH:29]=[CH:28][C:27]([C:30]([F:33])([F:32])[F:31])=[CH:26][CH:25]=1)([O-])=O>>[NH2:16][C:19]1[CH:23]=[CH:22][S:21][C:20]=1[C:24]1[CH:25]=[CH:26][C:27]([C:30]([F:33])([F:31])[F:32])=[CH:28][CH:29]=1

Participants

Reactant 2

HCID 18925402HCID 18925402, compound

HCID 18925417HCID 18925417, compound

Product 1

HCID 18925420HCID 18925420, compoundYield 70%

Procedure

The same procedures as described in Example 3 were carried out except that 3-nitro-2-(4-chlorophenyl)thiophene was replaced by 3-nitro-2-(4-trifluoromethylphenyl)thiophene. The yield was 70%. 1 H-NMR(CDCl3, δ value):4.00(2H, brs), 6.67(1H, d, J=5.1), 7.18(1H, d, J=5.1), 7.64(1H, s)

Sources & evidence

ORD record: ord-a1edc8cb9ab14759ad88e8df9490152b
Source dataset: uspto-grants-1998_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05747518

Reaction notes

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