Methanol, 1,1-diethoxy-, 1-acetate → 2-Acetylamino-6-methyl-1,2,4-triazolo[1,5-a]-1,3,5-triazine-7(6H)-thione
Reaction equation
[C:1]([NH:4][C:5]1[N:9]=[C:8]([NH2:10])[N:7]([C:11]([NH:13][CH3:14])=[S:12])[N:6]=1)(=[O:3])[CH3:2].[C:15](OC(OCC)OCC)(=O)C>>[C:1]([NH:4][C:5]1[N:9]=[C:8]2[N:10]=[CH:14][N:13]([CH3:15])[C:11](=[S:12])[N:7]2[N:6]=1)(=[O:3])[CH3:2]Participants
3
Procedure
The synthesis method of Example 55 was applied. The compound (1.02 g) obtained in Example 32 and diethoxymethyl acetate (10 ml) were used as reagents. The mixture was reacted at 100° C. for 5.5 hours to give 925 mg of white crystals (yield 87%).
Workup
- customThe synthesis method of Example 55
- customThe mixture was reacted at 100° C. for 5.5 hours
Sources & evidence
- ORD record
- ord-b68da1c1f70d4c80a710be83aa73fd56
- Source dataset
- uspto-grants-1998_05
- Patent number
- US05750545
Reaction notes
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