Cyclohexanecarbonyl chloride → 1-(4-Chlorobenzoyl)piperidin-4-one

HRID 129079

Reaction equation

HRID 129079 reaction equation

[CH:1]1([C:7]([N:9]2[CH2:14][CH2:13][C:12](=[O:15])[CH2:11][CH2:10]2)=[O:8])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.C1(C([Cl:24])=O)CCCCC1.O.Cl.N1CCC(=O)CC1>>[Cl:24][C:4]1[CH:5]=[CH:6][C:1]([C:7]([N:9]2[CH2:14][CH2:13][C:12](=[O:15])[CH2:11][CH2:10]2)=[O:8])=[CH:2][CH:3]=1

Participants

4

Reactant 3

HCID 75938Cyclohexanecarbonyl chloride

HCID 2723901Piperonylamine

HCID 193727331-(Cyclohexanecarbonyl)piperidin-4-one

Product 1

HCID 152314041-(4-Chlorobenzoyl)piperidin-4-one

Procedure

N-cyclohexanecarbonyl-4-piperidone from cyclohexanecarbonyl chloride and 4-piperidone hydrochloride hydrate. Colourless crystals.

Sources & evidence

ORD record: ord-b84e10d8ea824a9e947685aa1ae2224a
Source dataset: uspto-grants-1995_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05466687

Linked notes

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