3,5-Difluoropyridine → 3-[1-(5-Fluoro-pyridin-3-yl)-2-methyl-1H-imidazol-4-ylethynyl]-benzonitrile

HRID 1294516

Reaction equation

HRID 1294516 reaction equation
[CH3:1][C:2]1[NH:3][CH:4]=[C:5]([C:7]#[C:8][C:9]2[CH:10]=[C:11]([CH:14]=[CH:15][CH:16]=2)[C:12]#[N:13])[N:6]=1.[F:17][C:18]1[CH:19]=[N:20][CH:21]=[C:22](F)[CH:23]=1>>[F:17][C:18]1[CH:23]=[C:22]([N:3]2[CH:4]=[C:5]([C:7]#[C:8][C:9]3[CH:10]=[C:11]([CH:14]=[CH:15][CH:16]=3)[C:12]#[N:13])[N:6]=[C:2]2[CH3:1])[CH:21]=[N:20][CH:19]=1

Participants

3

Reactant 2

HCID 6428203,5-DifluoropyridineHCID 178432699HCID 178432699, compound

Product 1

HCID 668792883-[1-(5-Fluoro-pyridin-3-yl)-2-methyl-1H-imidazol-4-ylethynyl]-benzonitrile

Procedure

The title compound, MS: m/e=303.5 (M+), was prepared in accordance with the general method of example 1 from 3-(2-methyl-1H-imidazol-4-ylethynyl)-benzonitrile and 3,5-difluoro-pyridine.

Sources & evidence

ORD record
ord-3323023331a24b949037984d765f5e98
Source dataset
uspto-grants-2007_07
Patent number
US07241760B2

Linked notes

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