2-(2-nitrophenyl)-1H-imidazole → 2-(1H-Imidazol-2-yl)aniline
Reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[C:10]1[NH:11][CH:12]=[CH:13][N:14]=1)([O-])=O>[Pd].[Ni]>[NH:11]1[CH:12]=[CH:13][N:14]=[C:10]1[C:5]1[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=1[NH2:1]Participants
4
Reactant 1
Product 1
Reagents, catalysts & solvents 2
Procedure
By catalytic hydrogenation, using palladium on charcoal or Raney Nickel as catalyst, 2-(2-nitro-phenyl)-1H-imidazole, which is commercially obtainable, is converted into 2-(1H-imidazol-2-yl)-phenylaamine (U.S. Pat. No. 6,376,664).
Sources & evidence
- ORD record
- ord-9fd4041c4a4846e3988b66266169cd41
- Source dataset
- uspto-grants-2007_07
- Patent number
- US07241769B2
Reaction notes
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