HCID 69462383, compound → HCID 69459028, compound
Reaction equation
[NH:1]([C:3](=[O:18])[CH2:4][C:5]1[CH:13]=[C:12]([O:14][CH3:15])[C:11]([O:16][CH3:17])=[CH:10][C:6]=1[C:7](O)=[O:8])[NH2:2]>CC(O)=O>[CH3:15][O:14][C:12]1[C:11]([O:16][CH3:17])=[CH:10][C:6]2[C:7](=[O:8])[NH:2][NH:1][C:3](=[O:18])[CH2:4][C:5]=2[CH:13]=1Participants
3
Reactant 1
Product 1
Reagents, catalysts & solvents 1
Procedure
To 15 ml of AcOH at 100° C., add 1.5 g (5.9 mmol) of 2-(2-hydrazino-2-oxoethyl)-4,5-dimethoxy benzoic acid XI. After 5 minutes at 100° C., cool in an ice bath. Filter and wash twice with 1 ml of AcOH, twice with 2 ml of H2O, twice with 10 ml of Et2O.
Workup
- temperaturecool in an ice bath
- filtrationFilter
- washwash twice with 1 ml of AcOH, twice with 2 ml of H2O, twice with 10 ml of Et2O
Sources & evidence
- ORD record
- ord-33ad188f29cb4a7cbd359b780ae1146f
- Source dataset
- uspto-grants-2007_07
- Patent number
- US07250410B2
Reaction notes
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