HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,2-Difluoroacetyl chloride → HCID 25011857, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,2-Difluoroacetyl chloride | HCID 2736890 | — |
| Reactant | (1S,2R)-1-{[1-(4-fluorophenyl)-1H-indazol-5-yl]oxy}-1-phenylpropan-2-amine | HCID 66812640 | — |
| Product | HCID 25011857 | HCID 25011857 | — |
Reaction Steps
Prepared as described in Example 1 using (1S,2R)-1-{[1-(4-fluorophenyl)-1H-indazol-5-yl]oxy}-1-phenylpropan-2-amine (1a, 36 mg, 100 μmol) and difluoroacetyl chloride (29 mg, 300 μmol). Yield 40 mg (95%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07728030B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-07a7eb7b05044e3283da4d58a3c39cb0 |
| Source note | uspto-grants-2010_06 |