2-Hydrazinylpyrimidine → 5-Iodo-1-pyrimidin-2-yl-1H-indazole

HRID 13149

Reaction equation

[I:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[N:7]([C:11]1C=[CH:15][CH:14]=[CH:13][N:12]=1)[N:6]=[CH:5]2.[NH:17](C1N=CC=CN=1)N>>[I:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[N:7]([C:11]1[N:12]=[CH:13][CH:14]=[CH:15][N:17]=1)[N:6]=[CH:5]2

Participants

Reactant 2

HCID 3465582-Hydrazinylpyrimidine

HCID 593397925-iodo-1-pyridin-2-yl-1H-indazole

Product 1

HCID 593398145-Iodo-1-pyrimidin-2-yl-1H-indazole

Procedure

Prepared as described for 118b using 2-hydrazinopyrimidine. Yield 296 mg (24%).

Workup

customPrepared

Sources & evidence

ORD record: ord-4a60eb54c7244f049fd9118ffad58d33
Source dataset: uspto-grants-2010_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07728030B2

Linked notes

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