HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → Paclitaxel
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | DTPA paclitaxel | HCID 86583879 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Paclitaxel | HCID 36314 | — |
Reaction Steps
The sodium salt of DTPA-paclitaxel was also obtained by adding a solution of DTPA-paclitaxel in ethanol into an equivalent amount of 0.05 M NaHCO3, followed by lyophilizing to yield a water-soluble solid powder (solubility>20 mg equivalent paclitaxel/ml).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07384977B2 |
| Source dataset | uspto-grants-2008_06 |
| ORD ID | ord-68a1b04f08a14dc8b77820cd50f64b15 |
| Source note | uspto-grants-2008_06 |