4-(Methylthio)phenol → 5-(4-Dimethylcarbamoyl-phenoxy)-6-(4-methylsulfanyl-phenoxy)-2-pyridin-2-yl-1H-benzimidazole

HRID 13236

Reaction equation

HRID 13236 reaction equation
[CH3:1][N:2]([CH3:34])[C:3]([C:5]1[CH:33]=[CH:32][C:8]([O:9][C:10]2[C:24]([O:25][C:26]3[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=3)=[CH:23][C:13]3[NH:14][C:15]([C:17]4[CH:22]=[CH:21][CH:20]=[CH:19][N:18]=4)=[N:16][C:12]=3[CH:11]=2)=[CH:7][CH:6]=1)=[O:4].[CH3:35][S:36]C1C=CC(O)=CC=1>>[CH3:1][N:2]([CH3:34])[C:3]([C:5]1[CH:6]=[CH:7][C:8]([O:9][C:10]2[C:24]([O:25][C:26]3[CH:27]=[CH:28][C:29]([S:36][CH3:35])=[CH:30][CH:31]=3)=[CH:23][C:13]3[NH:14][C:15]([C:17]4[CH:22]=[CH:21][CH:20]=[CH:19][N:18]=4)=[N:16][C:12]=3[CH:11]=2)=[CH:32][CH:33]=1)=[O:4]

Participants

3

Reactant 2

HCID 140864-(Methylthio)phenolHCID 231456165-(4-Dimethylcarbamoyl-phenoxy)-6-phenoxy-2-pyridin-2-yl-1H-benzimidazole

Product 1

HCID 231454095-(4-Dimethylcarbamoyl-phenoxy)-6-(4-methylsulfanyl-phenoxy)-2-pyridin-2-yl-1H-benzimidazole

Procedure

The entitled compound was obtained in the same method as in Example 1 or in accordance with the method or by combining it with an ordinary method but using 4-fluoro-5-(4-dimethylcarbamoyl-phenoxy)-2-nitro-phenylamine obtained in Example 18 and 4-methylmercapto-phenol.

Workup

  1. customThe entitled compound was obtained in the same method as in Example 1 or in accordance with the method

Sources & evidence

ORD record
ord-8bfe42d6f2e54c90b4eeba49656a9ee9
Source dataset
uspto-grants-2010_06
Patent number
US07728025B2

Linked notes

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