tert-Butyl 8-(cyclopropylmethylene)-2-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[1,5-alpha]pyrazine-7(8H)-carboxylate → 7-N-(tert-Butoxycarbonyl)-8-(cyclopropylmethyl)-2-(trifluoromethyl)-5,6,7,8-tetrahydro[1,2,4]triazolo[1,5-alpha]pyrazine
Reaction equation
[CH:1]1([CH:4]=[C:5]2[N:10]([C:11]([O:13][C:14]([CH3:17])([CH3:16])[CH3:15])=[O:12])[CH2:9][CH2:8][N:7]3[N:18]=[C:19]([C:21]([F:24])([F:23])[F:22])[N:20]=[C:6]23)[CH2:3][CH2:2]1>[Pd].C(O)C>[C:14]([O:13][C:11]([N:10]1[CH2:9][CH2:8][N:7]2[N:18]=[C:19]([C:21]([F:23])([F:22])[F:24])[N:20]=[C:6]2[CH:5]1[CH2:4][CH:1]1[CH2:2][CH2:3]1)=[O:12])([CH3:17])([CH3:15])[CH3:16]Participants
4
