5-(2-Ethoxycarbonyl-phenoxy)-6-(4-methanesulfonyl-phenoxy)-2-pyridin-2-yl-1H-benzimidazole → 5-(Pyridin-2-yloxy)-2-pyridin-2-yl-6-(4-methanesulfonyl-phenoxy)-1H-benzimidazole

HRID 13335

Reaction equation

HRID 13335 reaction equation
C(OC([C:6]1[CH:38]=[CH:37][CH:36]=C[C:7]=1[O:8][C:9]1[C:23]([O:24][C:25]2[CH:30]=[CH:29][C:28]([S:31]([CH3:34])(=[O:33])=[O:32])=[CH:27][CH:26]=2)=[CH:22][C:12]2[NH:13][C:14]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][N:17]=3)=[N:15][C:11]=2[CH:10]=1)=O)C.OC1C=CC=C[N:41]=1>>[N:41]1[CH:36]=[CH:37][CH:38]=[CH:6][C:7]=1[O:8][C:9]1[C:23]([O:24][C:25]2[CH:26]=[CH:27][C:28]([S:31]([CH3:34])(=[O:32])=[O:33])=[CH:29][CH:30]=2)=[CH:22][C:12]2[NH:13][C:14]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][N:17]=3)=[N:15][C:11]=2[CH:10]=1

Participants

3

Reactant 2

HCID 231451405-(2-Ethoxycarbonyl-phenoxy)-6-(4-methanesulfonyl-phenoxy)-2-pyridin-2-yl-1H-benzimidazoleHCID 178516071HCID 178516071, compound

Product 1

HCID 231455785-(Pyridin-2-yloxy)-2-pyridin-2-yl-6-(4-methanesulfonyl-phenoxy)-1H-benzimidazole

Procedure

The entitled compound was obtained as a brown solid in the same method as in Example 14 or in accordance with the method or by combining it with an ordinary method but using 5-fluoro-4-(4-methanesulfonyl-phenoxy)-2-nitro-phenylamine obtained in Example 14 and 2-hydroxypyridine.

Workup

  1. customThe entitled compound was obtained as a brown solid in the same method as in Example 14 or in accordance with the method

Sources & evidence

ORD record
ord-fe85b7d4676e4898b334787d94c1f314
Source dataset
uspto-grants-2010_06
Patent number
US07728025B2

Linked notes

Loading…