HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Hydroxybenzoic Acid → 4-Hydroxy-3-iodobenzoic acid (2IPCOOH)
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Hydroxybenzoic Acid | HCID 135 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | Sodium Iodide | HCID 5238 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Sodium Hypochlorite | HCID 23665760 | — |
| Solvent | Water | HCID 962 | — |
| Product | 4-Hydroxy-3-iodobenzoic acid (2IPCOOH) | HCID 449473 | — |
Reaction Steps
30 g of 4-hydroxybenzoic acid are placed in 780 ml of water containing 18 g of sodium hydroxide, 49.5 g of sodium iodide are added, 675 ml of 3.5% sodium hypochlorite solution are run in slowly and the mixture is left with stirring at AT for 13 hours. 60 ml of concentrated H2SO4 are added and then, after cooling, the precipitate formed is filtered off and washed with water. This gives 32.46 g of the expected compound, m.p.=163° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07390924B2 |
| Source dataset | uspto-grants-2008_06 |
| ORD ID | ord-f4bd56211cd14a3fb5d2d390152a6732 |
| Source note | uspto-grants-2008_06 |