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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 13376Generated: October 27, 2026

2,3-Difluorobenzonitrile → 3-Fluoro-4-(2-fluoro-6-cyano-phenoxy)-phenylamine

https://huagongshe.com/reaction/13376

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,3-DifluorobenzonitrileHCID 88935—
Reactanttert-Butyl (3-Fluoro-4-hydroxyphenyl)carbamateHCID 11708410—
Product3-Fluoro-4-(2-fluoro-6-cyano-phenoxy)-phenylamineHCID 23145507—

Reaction Steps

The entitled compound was obtained in the same method as in Example 221 (step 1) or in accordance with the method or by combining it with an ordinary method but using tert-butyl (3-fluoro-4-hydroxy-phenyl)-carbamate obtained in Example 196 (step 1) and 1,2-difluoro-3-cyano-benzene.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07728025B2
Source datasetuspto-grants-2010_06
ORD IDord-414d8a4d43ff49a59592db1cbfed2ad3
Source noteuspto-grants-2010_06