4-(5-amino-2-fluorophenyl)-5,5-difluoro-4-methyl-6H-1,3-oxazin-2-amine → N-[3-(2-amino-5,5-difluoro-4-methyl-6H-1,3-oxazin-4-yl)-4-fluorophenyl]-4-chloro-5-cyclopropyl-1H-pyrazole-3-carboxamide
Reaction equation
[Cl:19][c:20]1[c:21]([C:28](=[O:29])[OH:30])[nH:22][n:23][c:24]1[CH:25]1[CH2:26][CH2:27]1.[NH2:1][c:2]1[cH:3][cH:4][c:5]([F:18])[c:6]([C:8]2([CH3:17])[N:9]=[C:10]([NH2:16])[O:11][CH2:12][C:13]2([F:14])[F:15])[cH:7]1>>[NH:1]([c:2]1[cH:3][cH:4][c:5]([F:18])[c:6]([C:8]2([CH3:17])[N:9]=[C:10]([NH2:16])[O:11][CH2:12][C:13]2([F:14])[F:15])[cH:7]1)[C:28]([c:21]1[c:20]([Cl:19])[c:24]([CH:25]2[CH2:26][CH2:27]2)[n:23][nH:22]1)=[O:29]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-2d6fdd90d5034303bd8f4743da1a41d8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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