2,2,2-Trifluoroethyl Methanesulfonate → [5-(4-Isopropyl-piperazine-1-carbonyl)-1-(2,2,2-trifluoro-ethyl)-1H-indol-2-yl]-[4-(piperidine-1-sulfonyl)-piperazin-1-yl]-methanone
Reaction equation
[CH3:38][S:39]([O:40][CH2:43][C:44]([F:45])([F:46])[F:47])(=[O:41])=[O:42].[CH:1]([CH3:2])([CH3:3])[N:4]1[CH2:5][CH2:6][N:7]([C:10](=[O:11])[c:12]2[cH:13][c:14]3[cH:15][c:16]([C:21](=[O:22])[N:23]4[CH2:24][CH2:25][N:26]([S:29](=[O:30])(=[O:31])[N:32]5[CH2:33][CH2:34][CH2:35][CH2:36][CH2:37]5)[CH2:27][CH2:28]4)[nH:17][c:18]3[cH:19][cH:20]2)[CH2:8][CH2:9]1>>[CH:1]([CH3:2])([CH3:3])[N:4]1[CH2:5][CH2:6][N:7]([C:10](=[O:11])[c:12]2[cH:13][c:14]3[cH:15][c:16]([C:21](=[O:22])[N:23]4[CH2:24][CH2:25][N:26]([S:29](=[O:30])(=[O:31])[N:32]5[CH2:33][CH2:34][CH2:35][CH2:36][CH2:37]5)[CH2:27][CH2:28]4)[n:17]([CH2:43][C:44]([F:45])([F:46])[F:47])[c:18]3[cH:19][cH:20]2)[CH2:8][CH2:9]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-95f17a64935f414bbbcc8a466b588817
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)