1-(2,3-Dihydro-1H-inden-4-yl)piperazine → 7-[4-(4-Indan-4-yl-piperazin-1-yl)-butoxy]-5-methyl-3,4-dihydro-1H-[1,8]naphthyridin-2-one

HRID 134304

Reaction equation

HRID 134304 reaction equation
[CH2:19]1[CH2:20][CH2:21][c:22]2[c:23]([N:28]3[CH2:29][CH2:30][NH:31][CH2:32][CH2:33]3)[cH:24][cH:25][cH:26][c:27]21.[CH3:1][c:2]1[cH:3][c:4]([O:13][CH2:14][CH2:15][CH2:16][CH:17]=[O:18])[n:5][c:6]2[c:11]1[CH2:10][CH2:9][C:8](=[O:12])[NH:7]2>>[CH3:1][c:2]1[cH:3][c:4]([O:13][CH2:14][CH2:15][CH2:16][CH2:17][N:31]2[CH2:30][CH2:29][N:28]([c:23]3[c:22]4[c:27]([cH:26][cH:25][cH:24]3)[CH2:19][CH2:20][CH2:21]4)[CH2:33][CH2:32]2)[n:5][c:6]2[c:11]1[CH2:10][CH2:9][C:8](=[O:12])[NH:7]2

Participants

3

Reactant 2

HCID 184748291-(2,3-Dihydro-1H-inden-4-yl)piperazineHCID 210733504-(4-Methyl-7-oxo-5,6,7,8-tetrahydro-[1,8]naphthyridin-2-yloxy)-butyraldehyde

Product 1

HCID 210738017-[4-(4-Indan-4-yl-piperazin-1-yl)-butoxy]-5-methyl-3,4-dihydro-1H-[1,8]naphthyridin-2-one

Sources & evidence

ORD record
ord-8e09b3caa98b4d66b80b467d39be9bf0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

Loading…