4'-Hydroxyacetophenone → N-(3-{1-[6-(4-Acetylphenoxy)-6-(2-fluorophenyl)hexyl]-4-piperidinyl}phenyl)-2-methylpropanamide

HRID 134333

Reaction equation

HRID 134333 reaction equation
[CH3:1][C:2](=[O:3])[c:4]1[cH:5][cH:6][c:7]([OH:8])[cH:9][cH:10]1.[F:11][c:12]1[c:13]([CH:18]([CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][N:24]2[CH2:25][CH2:26][CH:27]([c:30]3[cH:31][c:32]([NH:36][C:37]([CH:38]([CH3:39])[CH3:40])=[O:41])[cH:33][cH:34][cH:35]3)[CH2:28][CH2:29]2)[OH:42])[cH:14][cH:15][cH:16][cH:17]1>>[CH3:1][C:2](=[O:3])[c:4]1[cH:5][cH:6][c:7]([O:8][CH:18]([c:13]2[c:12]([F:11])[cH:17][cH:16][cH:15][cH:14]2)[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][N:24]2[CH2:25][CH2:26][CH:27]([c:30]3[cH:31][c:32]([NH:36][C:37]([CH:38]([CH3:39])[CH3:40])=[O:41])[cH:33][cH:34][cH:35]3)[CH2:28][CH2:29]2)[cH:9][cH:10]1

Participants

3

Reactant 2

HCID 74694'-HydroxyacetophenoneHCID 22048705N-(3-(1-[6-(2-fluorophenyl)-6-hydroxyhexyl]-4-piperidinyl}phenyl)-2-methylpropanamide

Product 1

HCID 22049366N-(3-{1-[6-(4-Acetylphenoxy)-6-(2-fluorophenyl)hexyl]-4-piperidinyl}phenyl)-2-methylpropanamide

Sources & evidence

ORD record
ord-dd43f48e74cd48b3a67e798d4bf03c9e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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