2-Chloro-5-ethynylpyridine → 5-ethynyl-N-methylpyridin-2-amine

HRID 1350677

Reaction equation

HRID 1350677 reaction equation
I[C:2]1[CH:3]=[CH:4][C:5]([NH:8][CH3:9])=[N:6][CH:7]=1.Cl[C:11]1[CH:16]=CC(C#C)=CN=1>>[C:11]([C:2]1[CH:3]=[CH:4][C:5]([NH:8][CH3:9])=[N:6][CH:7]=1)#[CH:16]

Participants

3

Reactant 2

HCID 106542812-Chloro-5-ethynylpyridineHCID 11253290(5-Iodo-pyridin-2-yl)-methyl-amine

Product 1

HCID 226631285-ethynyl-N-methylpyridin-2-amine

Procedure

(5-Ethynyl-pyridin-2-yl)-methyl-amine was prepared from (5-iodo-pyridin-2-yl)-methyl-amine in the same manner as 2-chloro-5-ethynyl-pyridine (Example 1).

Sources & evidence

ORD record
ord-c6617d5c137245319ac4d159989d388b
Source dataset
uspto-grants-2007_05
Patent number
US07214802B2

Linked notes

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