2-Chloro-5-ethynylpyridine → 5-Ethynyl-N,N-dimethylpyridin-2-amine

HRID 1350688Notes

Reaction equation

HRID 1350688 reaction equation
I[C:2]1[CH:3]=[CH:4][C:5]([N:8]([CH3:10])[CH3:9])=[N:6][CH:7]=1.Cl[C:12]1[CH:17]=CC(C#C)=CN=1>>[C:12]([C:2]1[CH:3]=[CH:4][C:5]([N:8]([CH3:10])[CH3:9])=[N:6][CH:7]=1)#[CH:17]

Participants

3

Reactant 2

HCID 106542812-Chloro-5-ethynylpyridineHCID 234385795-Iodo-N,N-dimethylpyridin-2-amine

Product 1

HCID 210973505-Ethynyl-N,N-dimethylpyridin-2-amine

Procedure

(5-Ethynyl-pyridin-2-yl)-dimethyl-amine was prepared from (5-iodo-pyridin-2-yl)-dimethyl-amine in the same manner as 2-chloro-5-ethynyl-pyridine (Example 1).

Sources & evidence

ORD record
ord-2c4cc57046e24d0bb0cf4c459f2632e3
Source dataset
uspto-grants-2007_05
Patent number
US07214802B2

Reaction notes

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